Who We Are

3Scan is turning tissue biology and histopathology into data science, giving researchers the insights they need to break new ground.

A one-stop shop for digital and computational pathology, 3Scan’s KESM produces digital 3D tissue models with micron-scale resolution at 400 times the throughput of traditional microscopes.

3Scan’s data platform enables quantitative image analysis of diseases like cancer, Parkinson’s, Alzheimer’s, and Huntington’s, opening up the potential for new diagnostic and therapeutic solutions.

Founded by Todd Huffman, Megan Klimen, Matthew Goodman, and Cody Daniel in San Francisco in 2011, 3Scan’s team of engineers, biologists and data-scientists is expanding its work into a suite of digital tools that will allow instant identification and classification of histopathologic features and tissue structures.

3Scan FAQ


We have a tiered pricing structure with heavy discounts for researchers who are looking to publish their data. Please contact us at info@3Scan.com for more details.

Using new technologies to expand current understanding of tissue biology, we’re enabling the next generation of medical and biotech research. Customers send us tissue samples and we handle the staining, embedding, sectioning, image acquisition, image processing, and analysis.

The last 200 years have seen extraordinary changes in the technologies used for molecular biology research and diagnostics, but the conventional pathology workflow is basically the same as it was in the 1800s. Pathology looks more like an art form than a science: subjective, qualitative, and manual.

This lack of innovation in histology and pathology leads to real-life consequences for patients. Widespread sampling bias leads to missed and misdiagnosis, putting lives at risk. It has implications at the societal level, too. Irreproducible research contributes to an estimated $28 billion in costs every year.

3Scan’s technology brings precision, repeatability, and analysis to pathology for the first time, delivering the insights both patients and society needs.

Knife-Edge Scanning Microscopy (KESM) is 3Scan’s propriety robotic imaging platform that produces digital 3D tissue models at micron-scale resolution using a diamond knife, nano-positioned motions, and proprietary optics.
KESM delivers trillions of voxels per day at 400 times the throughput of traditional microscopy.

We stain our samples using whole mount staining protocols before the tissue is sectioned and imaged.

Yes! We can. We’re also working on several form functions that could allow for downstream molecular applications. Get in touch with us to talk about how we can help.

3Scan’s primary customers are researchers and pharmaceutical companies. We’re not doing tissue diagnostics for hospital pathologists at this time.

Both, and neither. Our microscopes, data platform, and team of engineers, biologists and data-scientists handle all of your imagining and analysis needs.

Load More


2018 – 3Scan and Prellis join to 3D print tissue

2018 – NIH Grant

2016 – Series B closes ($14M)

2015 – Series A closes ($8M)

2012 – Breakout Labs ($350K)

2012 – Commercial system built

2011 – DARPA becomes 1st customer ($30K)

2011 – Founding investment ($150K)

2010 – 3Scan spins-off Texas A&M Brain Network

2008 – Patent (US 6,744,572) is licensed to 3Scan

2004 – NSF & NIH grant ($1.6M) funds invention of the KESM