About

Mission

3Scan is forging the 3D atlas of the biological world enabling unique insights into physiologic and pathologic processes.

Who We Are

3Scan is turning tissue biology and histopathology into data science, giving researchers the insights they need to break new ground.

A one-stop shop for digital and computational pathology, 3Scan’s KESM produces digital 3D tissue models with micron-scale resolution at 400 times the throughput of traditional microscopes.

3Scan’s data platform enables quantitative image analysis of diseases like cancer, Parkinson’s, Alzheimer’s, and Huntington’s, opening up the potential for new diagnostic and therapeutic solutions.

Founded by Todd Huffman, Megan Klimen, Matthew Goodman, and Cody Daniel in San Francisco in 2011, 3Scan’s team of engineers, biologists and data-scientists is expanding its work into a suite of digital tools that will allow instant identification and classification of histopathologic features and tissue structures.

FAQ

about

We have a tiered pricing structure with heavy discounts for researchers who are looking to publish their data. Please contact us at info@3Scan.com for more details.

Using new technologies to expand current understanding of tissue biology, we’re enabling the next generation of medical and biotech research. Customers send us tissue samples and we handle the staining, embedding, sectioning, image acquisition, image processing, and analysis.

The last 200 years have seen extraordinary changes in the technologies used for molecular biology research and diagnostics, but the conventional pathology workflow is basically the same as it was in the 1800s. Pathology looks more like an art form than a science: subjective, qualitative, and manual.

This lack of innovation in histology and pathology leads to real-life consequences for patients. Widespread sampling bias leads to missed and misdiagnosis, putting lives at risk. It has implications at the societal level, too. Irreproducible research contributes to an estimated $28 billion in costs every year.

3Scan’s technology brings precision, repeatability, and analysis to pathology for the first time, delivering the insights both patients and society needs.

Knife-Edge Scanning Microscopy (KESM) is 3Scan’s propriety robotic imaging platform that produces digital 3D tissue models at micron-scale resolution using a diamond knife, nano-positioned motions, and proprietary optics.
KESM delivers trillions of voxels per day at 400 times the throughput of traditional microscopy.

We stain our samples using whole mount staining protocols before the tissue is sectioned and imaged.

Yes! We can. We’re also working on several form functions that could allow for downstream molecular applications. Get in touch with us to talk about how we can help.

3Scan’s primary customers are researchers and pharmaceutical companies. We’re not doing tissue diagnostics for hospital pathologists at this time.

Both, and neither. Our microscopes, data platform, and team of engineers, biologists and data-scientists handle all of your imagining and analysis needs.

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Milestones

2004 – NSF & NIH grant ($1.6M) funds invention of the KESM

2008 – Patent (US 6,744,572) is licensed to 3Scan

2010 – 3Scan spins-off Texas A&M Brain Network

2011 – Founding investment ($150K)

2011 – DARPA becomes 1st customer ($30K)

2012 – Commercial system built

2012 – Breakout Labs ($350K)

2015 – Series A closes ($8M)

2016 – Series B closes ($14M)

Our Team

Todd Huffman

CEO

CEO Todd Huffman has worked with the technology behind 3Scan since 2005. He collaborated with the late Bruce McCormick and Brain Networks Laboratory, where KESM technology was developed, to shed light on neural architectures and computation. With a bachelor’s in neuroscience and master’s in bioinformatics, Todd co-founded 3Scan in 2011 and has worked diligently to expand the technology, applications, funding, and talented team the company boasts today. Todd has an intense nostalgia for the future and passionately pursues technological solutions to a variety of problems, which has led to years of work on developing cryonics protocols, creating experimental sensory body modification, running projects for DARPA in Afghanistan, assisting human rights activists against oppressive governments, and running technology and culture events such as BIL (a free analog to the TED conference). He has also done work for World Bank and various NGOs.

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Todd Huffman

Todd Huffman

CEO

Megan Klimen

COO

Without Megan 3Scan would grind to a halt. Executing roles of CFO, damage control, and manager, she keeps the daily flow of the company moving along while handling the details at all ends. Studying biology and anthropology at UC San Diego, she’s been involved running a wide range of projects over the years in all corners of the world, including helping found and run the BIL Conference series. She is heavily involved in Start-up Chile and represents 3Scan in all it’s endeavors.

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Megan Klimen

Megan Klimen

COO

Matthew Goodman

CTO

Data Wrangler Extraordinaire, MattyG keeps the bits shuffling and is responsible for the entirety of the software and processing supporting our microscope technology. Coming out of a Materials Science background at the University of Arizona and Biomedical Engineering program at UT Austin, Matthew is the lead software architect at 3Scan.  He’s currently taking time off from his Ph.D. in Biomedical Engineering at UT Austin to follow through with building 3Scan from the ground up.

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Matthew Goodman

Matthew Goodman

CTO

Cody Daniel

Master Chief Engineer

Hailing from a long line of hardware hackers, Cody is tracking on the development of the physical systems at 3Scan as Master Chief Engineer.  His background is in Mechanical Engineering and Materials Science at MIT, with significant time spent learning how to break and debug systems in a wide range of personal projects.  He moved to SF after graduation to follow the dream of a start-up cowboy by working at 3Scan.

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Cody Daniel

Cody Daniel

Master Chief Engineer

Steve England

Chief Scientific Officer
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Steve England

Steve England

Chief Scientific Officer

Ben Mossbarger

Optical Engineer

Ben studied the secret language of the photons at the University of Toronto’s Department of Physics and Institute of Optical Sciences, where he received his Master’s in 2011. After two years’ doctoral research studying ultrafast laser interactions with nanomaterials, Ben flew the coop to find new opportunities outside academia. Having joined the 3Scan team in spring 2014, he now spends his days fiddling with our optics and coaxing light into our microscope.

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Ben Mossbarger

Ben Mossbarger

Optical Engineer

Katy Pelton

Director of Imaging

Katy is the lab manager for 3Scan. Prior to 3Scan Katy studied biology and psychology in her school years. After college Katy worked in operations/administrations for a large health clinic.

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Katy Pelton

Katy Pelton

Director of Imaging

Gerald Spencer

Director of Production Engineering

Gerald was trained as a mechanical engineer, while sailing all around the Pacific. His strengths shine as our machinery health wizard by tracking the variety of parameters that affect the quality of our sample slicing. Most would consider his background from the California Maritime Academy a little displaced from microscopy, but this couldn’t be further from the truth. Being an engineer at sea has taught Gerald how to think on his feet to solve a variety of problems, while honing his skills as a machinist. Beyond this, his background is incredibly diverse, ranging from biomechanical testing laboratories to DOE funded wind turbine research. We think he’ll be helping our scopes achieve the perfect slice for years to come!

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Gerald Spencer

Gerald Spencer

Director of Production Engineering

Squirrel Collins

Microscope Operator

Squirrel wants to live in a world where her brain data is available in bits, her penpal lives on Mars, and a robot delivers her tea. As Director of 3Scan’s Human Welfare Division, she is that friend who helps you move the bodies and hires the cleaner afterwards. With a background in paleontology and auction management, Squirrel brings a diverse variety of skills into the mix.

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Squirrel Collins

Squirrel Collins

Microscope Operator

Caroline "mills" Miller

Director of Biology

In her 18 year science career Caroline has gained valuable experience from a clinical pathology and associated mortuary lab in London, a breast cancer research lab at UCSF and 7 years running the Gladstone Institutes Histology and Light Microscopy Core. Using experience gained in all these different pathology modalities and years of managing volunteers in many large projects, she brings a wealth of tissue, people and process handling skills to 3Scan.

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Caroline

Caroline "mills" Miller

Director of Biology

Ted Scharff

Acquisition Lead
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Ted Scharff

Ted Scharff

Acquisition Lead

Kristy Parker

Histology Project Manager
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Kristy Parker

Kristy Parker

Histology Project Manager

Tess Aquarium

Office Manager
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Tess Aquarium

Tess Aquarium

Office Manager

Trevor Ellermann

Technical Operations Consultant
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Trevor Ellermann

Trevor Ellermann

Technical Operations Consultant

Debbie Toburen

VP of Product
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Debbie Toburen

Debbie Toburen

VP of Product

Pranathi Vemuri

Data Scientist
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Pranathi Vemuri

Pranathi Vemuri

Data Scientist

Sara Brockmueller

Software Engineer
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Sara Brockmueller

Sara Brockmueller

Software Engineer

Sam Brewczynski

Production Engineer
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Sam Brewczynski

Sam Brewczynski

Production Engineer

Nada Rastad

General Counsel
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Nada Rastad

Nada Rastad

General Counsel

Navid Farahani

Chief Medical Information Officer
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Navid Farahani

Navid Farahani

Chief Medical Information Officer

Liz Raible

Project Manager
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Liz Raible

Liz Raible

Project Manager

Morgan Martinez

Research Chemist
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Morgan Martinez

Morgan Martinez

Research Chemist

Ilica Mahajan

Software Engineer
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Ilica Mahajan

Ilica Mahajan

Software Engineer

Terri Hnatyszyn

VP of Marketing
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Terri Hnatyszyn

Terri Hnatyszyn

VP of Marketing

Hameed Tasal

Customer Success Manager
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Hameed Tasal

Hameed Tasal

Customer Success Manager

Sam Gawthrop

DevOps Engineer
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Sam Gawthrop

Sam Gawthrop

DevOps Engineer

Dylan Jutt

Senior Animator
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Dylan Jutt

Dylan Jutt

Senior Animator

Crutcher Dunnavant

Senior Software Engineer
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Crutcher Dunnavant

Crutcher Dunnavant

Senior Software Engineer

Alex Braun

Interfaces Engineer
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Alex Braun

Alex Braun

Interfaces Engineer

Avi Goldberg

Web Lead
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Avi Goldberg

Avi Goldberg

Web Lead

Chris Rhodes

Senior Engineer
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Chris Rhodes

Chris Rhodes

Senior Engineer

Corey Monteith

Scientific Strategy and Design
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Corey Monteith

Corey Monteith

Scientific Strategy and Design

Scott Jenkins

Head of Sales & Growth
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Scott Jenkins

Scott Jenkins

Head of Sales & Growth

AC Gillette

Software Engineer
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AC Gillette

AC Gillette

Software Engineer

Kat Scott

Analysis Lead
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Kat Scott

Kat Scott

Analysis Lead

Wesley Graybill

Software Engineer
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Wesley Graybill

Wesley Graybill

Software Engineer

Hunter Jackson

Data Scientist
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Hunter Jackson

Hunter Jackson

Data Scientist

Stephanie Stewart Bailey

HR Manager
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Stephanie Stewart Bailey

Stephanie Stewart Bailey

HR Manager

Joey Springer

R&D Hardware Engineer
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Joey Springer

Joey Springer

R&D Hardware Engineer

Michael Devine

Imaging Software Engineer
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Michael Devine

Michael Devine

Imaging Software Engineer